Dental implants more successful if higher level of vitamin D – Sept 2016

Is Low Serum Vitamin D Associated with Early Dental Implant Failure? A Retrospective Evaluation on 1625 Implants Placed in 822 Patients

Mediators of Inflammation, Vol 2016, Article ID 5319718, 7 pages, http://dx.doi.org/10.1155/2016/5319718
Francesco Mangano,1 Carmen Mortellaro,2 Natale Mangano,3 and Carlo Mangano4
1Department of Surgical and Morphological Science, Dental School, University of Insubria, 21100 Varese, Italy
2Department of Health Sciences, University of Eastern Piedmont, 28100 Novara, Italy
3Division of Endocrinology and Metabolism, Moriggia Pelascini Hospital, 22015 Gravedona ed Uniti, Italy
4Department of Dental Sciences, University Vita Salute San Raffaele, 20132 Milan, Italy

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Aim. To investigate whether there is a correlation between early dental implant failure and low serum levels of vitamin D. Methods. All patients treated with dental implants in a single centre, in the period 2003–2015, were considered for enrollment in this study. The main outcome was early implant failure. The influence of patient-related variables on implant survival was calculated using the Chi-square test. Results. 822 patients treated with 1625 implants were selected for this study; 27 early failures (3.2%) were recorded. There was no link between gender, age, smoking, history of periodontitis, and an increased incidence of early failures. Statistical analysis reported 9 early failures (2.2%) in patients with serum levels of vitamin D > 30 ng/mL, 16 early failures (3.9%) in patients with levels between 10 and 30 ng/mL, and 2 early failures (9.0%) in patients with levels <10 ng/mL. Although there was an increasing trend in the incidence of early implant failures with the worsening of vitamin D deficiency, the difference between these 3 groups was not statistically significant (). Conclusions. This study failed in proving an effective link between low serum levels of vitamin D and an increased risk of early implant failure. Further studies are needed to investigate this topic.